Lub ntsiab Cheebtsam ntawm Protein Connective ntaub so ntswg

Collagen, yog qhov tseem ceeb ntawm cov protein nyob rau hauv extracellular matrix ntawm ntau yam ntaub so ntswg nyob rau hauv lub cev. Raws li qhov tseem ceeb ntawm cov ntaub so ntswg sib txuas, nws yog cov protein ntau tshaj plaws hauv cov tsiaj nyeg, suav txog 25% txog 35% ntawm cov ntsiab lus protein ntawm tag nrho lub cev. Collagen yog tsim los ntawm cov amino acids ua ke los tsim triple helical fibrils hu ua collagen helices. Nws feem ntau pom muaj nyob rau hauv cov ntaub so ntswg xws li pob txha mos, pob txha, tendons, ligaments thiab tawv nqaij.
Nyob ntawm qhov degree ntawm mineralization, cov ntaub so ntswg collagen tuaj yeem ua kom nruj (pob txha), ua raws (cov leeg), los yog muaj cov gradient los ntawm nruj mus rau raws li (pob txha mos). Nws kuj muaj ntau nyob rau hauv lub cornea, hlab ntsha, hnyuv, intervertebral discs, thiab dentin nyob rau hauv cov hniav. Hauv cov leeg nqaij, nws yog qhov tseem ceeb ntawm endomysium. Collagen ua rau 1-2% ntawm cov leeg nqaij thiab 6% ntawm qhov hnyav ntawm cov leeg muaj zog. Cov fibroblasts yog cov hlwb ntau tshaj plaws uas tsim collagen. Gelatin, uas yog siv rau hauv cov khoom noj thiab kev lag luam, muaj irreversibly hydrolyzed collagen. Collagen muaj ntau yam kev kho mob siv los kho cov pob txha thiab tawv nqaij.
Lub npe collagen yog muab los ntawm Greek κόλλ (Kolla), lub ntsiab lus "glue" thiab lub ntsiab lus - έν, -gen, lub ntsiab lus "los tsim". Qhov no yog hais txog kev siv thaum ntxov ntawm cov compound hauv cov txheej txheem ntawm boiling daim tawv nqaij thiab tendons ntawm nees thiab lwm yam tsiaj kom tau cov kua nplaum.