Collagen txawv
Collagen tuaj yeem muab faib ua: collagen molecules thiab me me molecules collagen peptide, glial feem ntau peb noj npua trotters, uas muaj collagen tab sis nws yog macromolecular protein, nws qhov hnyav molecular yog 300 txhiab ntau dua Dalton, thiab tsis yog los ntawm kev nqus ncaj qha ntawm tib neeg lub cev. thiab tus nqi nqus yog tsawg heev; thiab los ntawm alkali thiab enzyme digestion technology rau molecular yuag tswj nyob rau hauv 6000 Dalton nyob rau hauv lub collagen, hu ua collagen peptide yog nruab nrab ntawm cov amino acids thiab proteins, ib tug ntau ntawm peptide bonds los tsim ib tug peptide los tsim ob los yog ntau tshaj amino acid dehydration condensation, ntau peptide. multistage folding ntawm kev tsim cov protein molecule. Peptides yog cov khoom muaj protein ntau, uas cov molecules tsuas yog nanometer loj, thiab tau yooj yim nqus los ntawm lub plab, cov hlab ntsha thiab tawv nqaij, thiab lawv qhov nqus tau ntau dua li cov proteins macromolecular.
Collagen muaj nuj nqi
Qhov hnyav molecular ntawm 6000 Dalton collagen peptide, thiab muab faib ua 1000-6000 Dalton protein peptide thiab 1000 Dalton hauv cov protein peptide. Tus naj npawb ntawm cov amino acid uas muaj peptide feem ntau yog ob mus rau cuaj raws li tus naj npawb ntawm peptide amino acids nyob rau hauv ntau lub npe sib txawv: lub compound muaj ob amino acids thiab lub cev qhuav dej condensation hu ua ob peptide peptide, plaub thiab peb ntawm tsib peptides, peptide peptide tebchaw mus txog rau cuaj; feem ntau muaj 10 ~ 50 amino acid molecules peptide hu ua dehydration condensation.
Absorption thiab technology
Oligopeptides thiab peptides tuaj yeem nqus tau ncaj qha los ntawm lub cev, thaum peptides tsis yog Agar1953 tau lees paub qhov ua tiav ob lub peptide hauv nas plab hnyuv epithelial thauj, tab sis cuam tshuam los ntawm cov kev xav ntawm kev zom zaub mov thiab kev nqus, cov kws tshawb fawb ntawm lwm yam kev nqus tsis yooj yim rau lees txais, txog thaum xyoo 1960, Newey thiab Smyth (19591960) tau muab thawj qhov kev nqus ntawm peptide tau lees paub los ntawm cov ntaub ntawv molecular, cov nqi pes tsawg tuaj yeem ua tiav rau hauv cov hnyuv mucosa hlwb hauv 1000 Dalton peptide hauv kev lag luam, maj mam txais lub hom phiaj qhov tseeb. yog ua tiav peptide absorption. Xyoo 1995 Tuam Tshoj tus kws tshaj lij Le Guowei rau txoj hnyuv infusion ntawm casein hydrolyzate tom qab oligopeptide los ntawm HPLC kev tshawb pom ntawm oligopeptide tau pom tias cov ntshav siab portal leeg thiab cov hnyuv tau tshwm sim nyob rau hauv tib lub peptide peptide tuaj yeem cuam tshuam cov nqaij qaib plab hnyuv nqus tag thiab tuaj yeem nkag mus rau hauv cov ntshav. Qhov thib ob perfusion casein peptide hydrolyzate tom qab HPLC kuaj pom pom tias peptides ntawm lub siab portal leeg ntshav thiab plab hnyuv cov ntsiab lus tsuas yog tshwm sim me me ntawm cov peptide no pom tau tias peptide rau hauv lub cev kom tawg mus rau hauv oligopeptides tuaj yeem nqus tau los ntawm lub cev kom cov txheeb ze oligopeptide. zoo heev txo nws tus nqi nqus. Ntau qhov kev sim tshuaj ntsuam xyuas tau ua pov thawj tias kev thauj mus los ntawm oligopeptide hauv tib neeg lub cev yog qhov zoo dua li cov nqaij qaib, thiab qhov nqus ntawm oligo peptide yog 39.6% siab dua li cov nqaij qaib. Ib zaug ntxiv paub tseeb tias peptide tsis tuaj yeem dhau los ntawm kev zom zaub mov, lub siab nqus tau zoo heev txo lub nra ntawm lub siab, plab hnyuv loj txhim kho bioavailability; hluavtaws peptides tuaj yeem cuam tshuam ncaj qha rau tib neeg collagen yam tsis muaj kev puas tsuaj rau hauv cov amino acid thiab polypeptide ua lub luag haujlwm tsis yog mus txog.
